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Oxford Textbook of Clinical Pharmacology and Drug Therapyicon  
รหัส : 9780192632340
ยี่ห้อ : Oxford University Press
รุ่น : David Grahame-Smith, Jeffrey Aronson
ราคาปกติ :  3,999.00      
เว็บไซต์เกี่ยวข้อง :
รายละเอียดย่อ :
656 pages
116 line illus
276x219 mm
Publication date: 7 March 2002

รายละเอียดทั้งหมด :

Oxford Textbook of Clinical Pharmacology and Drug Therapy


  • 'Any clinical medical student or junior doctor will find this work enjoyable and useful. ' - Journal of the Royal Society of Medicine
  • 'The fact that a third edition has been produced is testimony to the value of the textbook and in general the authors should be congratulated on the clarity of the text... Overall, the text is well presented and I beleive a worthy addition for medical libraries. It will be a useful guide particularly for medical students and even, I would suggest, for those who have qualified. ' - Pharmaceutical Journal
  • 'The authors... have compiled a first-rate textbook... It provides an excellent bridge for medical students from the start of their clinical rotation right the way through to finals and beyond. This is a very useful book to have and definitely a worthwhile purchase. ' - GKT Gazette

  • Advice on practical matters of drug prescribing and applying clinical pharmacology to daily practice
  • Detailed descriptions of the practical management of diseases with drugs, emphasizing the integration of principles with practice
  • A ready-reference pharmacopoeia of over 300 commonly used drugs with details on their use
  • Completely updated, providing an evidence-based approach and best reference starting point for students
  • Clear explanations and definitions of concepts and terms
The Oxford Textbook of Clinical Pharmacology and Drug Therapy continues to provide medical students and clinicians with a unique insight into why drugs have their therapeutic effects, by presenting the basic pharmacological principles of pharmacology as they affect the patient. An understanding of these clinical pharmacological principles is essential for rational, safe, effective, and economical prescribing. The text shows how knowledge of the scientific basis of drug action is applied in a clinical context to devise the most effective treatments for disease and to maximize the therapeutic effects of the drugs being used.

This new edition includes an appraisal of the value of evidence-based medicine and a greater discussion of issues in genetics. There are specialist contributors for areas of infectious disease, gastrointestinal disorders, blood disorders, general anaesthesia, cancer chemotherapy, and immunosuppression. The revision also includes updates to both the pharmacopoeia and the drug therapy section to reflect new developments in both available drugs and ineir their use.

Readership: Primarily for clinical medical students but also used at postgraduate level and by clinicians.

Section 1
1. The four processes of drug therapy
1.2. The pharmacokinetic process
2. The pharmaceutical process: Is the drug getting into the patient?
2.2. Systematic availability (bioavailability)
2.3. Special drug formulations
3. The pharmacokinetic process: Is the drug getting to its site of action?
3.2. Drug distribution
3.3. Drug metabolism
3.4. Drug excretion
3.5. Simple pharmacokinetic calculations
3.6. The mathematics of pharmacokinetics
4. The pharmacodynamic process: Is the drug producing the required pharmacological effect?
4.2. Stereoisomerism and drug action
4.3. Graded responses to drugs: the dose-response curve in drug therapy
5. The therapeutic process: Is the pharmacological effect being translated into therapeutic effect?
5.2. Translation of the pharmacological effect of a drug into a therapeutic effect during long-term drug therapy
5.3. The aims of drug therapy
6. Practical applications of the analysis of drug therapy
6.2. The application of the processes of drug therapy in analysing failure to respond to treatment
7. Monitoring drug therapy
7.2. Monitoring the pharmacodynamic effects of drugs
7.3. Monitoring drug pharmacokinetics (plasma concentration measurement)
8. Pharmacogenetics and pharmacogenomics
8.2. Pharmacodynamic genetic variations
9. Adverse reactions to drugs
9.2. Incidence of adverse drug reactions
9.3. Classification of adverse drug reactions
9.4. Dose-related adverse drug reactions
9.5. Non-dose-related adverse drug reactions
9.6. Long-term and withdrawal effects causing adverse drug reactions
9.7. Delayed effects causing adverse drug reactions
9.8. Surveillance methods used in detecting adverse drug reactions
10. Drug interactions
10.2. Drugs likely to be involved in interactions
10.3. Pharmaceutical interactions
10.4. Pharmacokinetic interactions
10.5. Pharmacodynamic interactions
10.6. Lists clinically important drug interactions
11. Drug therapy in young and in old people
11.2. Drug therapy in old people
12. Drug therapy and reproduction
12.2. Hormone replacement therapy
12.3. The treatment of infertility
12.4. Drug therapy during pregnancy
12.5. Drug therapy in the termination of pregnancy and in the management of preterm labour and labour
12.6. Drug therapy and breast-feeding
13. Patient compliance
13.2. Methods of measuring compliance
13.3. Methods of improving compliance
14. Placebos
14.2. Factors that influence the response to placebos
14.3. Mode of action of placebos
14.4. Adverse effects of placebos
15. Drug discovery and development: the pharmaceutical industry and the regulatory authorities
15.2. Drug development
15.3. Post-marketing surveillance
15.4. Advertising
15.5. Regulatory authorities
15.6. Local drug and therapeutics committees
15.7. Drug costs
16. Clinical trials
16.2. The conduct of a clinical trial
16.3. Ethics
17. The drug history and the clinical examination and investigation of drug effects
17.1. Taking the drug history
17.2. Clinical examination and investigation of drug effects
17.3. The importance of good records and communication
Section 2
18. Principles of prescribing
18.2. Evidence - based medicine
18.3. How to choose a drug
19. How to write a prescription
19.2. Propriety names versus approved names
19.3. Prescribing controlled drugs
19.4. Repeat prescribing
19.5. Abbreviations
20. Sources of information on drugs
20.2. Pharmacokinetics
20.3. Pharmacological effects of drugs
20.4. Therapeutics
20.5. Pharmacogenetics
20.6. Adverse effects of drugs
20.7. Drug interactions
20.8. Clinical trials
20.9. Patient compliance
20.10. Prescribing information
20.11. Computerised databases
20.12. Drug information services
20.13. Bibliography
Section 3
21. Introduction to drug therapy
22.2. Chemotherapy of viral infections


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