Encyclopedia of The EYE/4Volume Set

As the first comprehensive reference for the eye, its support structures, diseases, and treatments, Encyclopedia of the Eye is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea and lens. It also covers the physiological and pathophysiologic processes that affect all eye tissues.

This encyclopedia is invaluable for graduate students and postdoctoral fellows who are seeking an introduction to an area of eye research. Each chapter explains the basic concepts and provides references to relevant chapters within the encyclopedia and more detailed articles across the wider research literature. The encyclopedia is also particularly useful for visual scientists and practitioners who are researching a new area, seeking deeper understanding of important research articles in fields adjacent to their own, or reviewing a grant outside their immediate area of expertise.

Key Features

• Written by experts at a level that permits students to grasp key elements of a specific subject
• Provides an entryway into the major features of current eye research
• No other source puts this much information, so well-indexed and with so many helpful full color figures and graphics, in the hands of the ophthalmic scientist

Table of Contents

	Article Title	Lead Author
1	Adaptive immune system and the eye: mucosal immunity	Austin Mircheff
2	Adaptive Immune System and the eye: T Cell-mediated immunity	Kyle McKenna
3	Innate Immune System and the eye	Meredith Gregory-Ksander
4	Role of Complement in Ocular Immune Response	Nalini Bora
5	Dynamic Immunoregulatory Processes that Sustain Immune Privilege in the Eye	Jerry Niederkorn
6	Immunosuppressive and Anti-Inflammatory Molecules that maintain Immune privilege of the Eye	Andy Taylor
7	Antigen Presenting Cells in the Eye and Ocular Surface	Pedram Hamrah
8	Angiogenesis in the Eye	Claus Cursiefen
9	Dry Eye: An Immune-Based Inflammation	Michael E. Stern
10	Penetrating Keratoplasty	D F P Larkin
11	Immunopathogenesis of HSV Keratitis	Robert Hendricks
12	Immunopathogenesis of Onchocerciasis (River Blindness)	Eric Pearlman
13	Immunopathogenesis of Pseudomonas Keratitis	Linda Hazlett
14	Pathogenesis and Immunology of Bacterial Endophthalmitis	Mike Gilmore
15	Immunobiology of Acanthamoeba Keratitis	Jerry Niederkorn
16	Immunopathogenesis of Experimental Uveitic Diseases	Rachel Caspi
17	Pathogenesis of Uveitis in Humans	John Forrester
18	Immunobiology of Age-related Macular Degeneration	Rafael Ufret-Vincenty
19	Molecular and Cellular Mechanisms in Allergic Conjunctivitis	Virginia Calder
20	Immunobiology of Uveal Melanoma	Martine Jager
22	Pathogenesis of Fungal Keratitis	Eric Pearlman
23	Lens Structure	David Beebe
24	Lens determination and induction	Richard Lang
25	Lens fiber cell differentation	Michael Robinson
28	Normal age-related changes - crystallin modifications, lens hardening	Kirsten Lampi
30	Lens regeneration	Panagiotis Tsonis
31	Structure and evolution of the crystallins	Graeme Wistow
32	Ionic Permeability and Currents in the Lens	Paul Donaldson
33	Gap junctions	Eric Beyer
36	Accommodation	Adrian Glasser
37	Genetics of congenital cataract	J. Fielding Hejtmancik
38	Cortical cataracts	Ralph Michael
39	Nuclear cataracts	Roger Truscott
40	Posterior subcapsular and anterior polar cataracts	Choun-ki Joo
42	Genetics of age-related cataracts	Alan Shiels
43	Posterior Capsule Opacification	I.M. Wormstone
45	Presbyopia	Adrian Glasser
46	The Epidemiology of Cataract	Sheila West
47	Tear film overview	Kazuo Tsubota
48	Meibomian glands and lipid layer	Thomas J. Millar
49	Lacrimal gland overview	Sarah Hamm-Alvarez
50	Lacrima gland hormonal regulation	Austin Mircheff
51	Lacrimal gland signaling - neural	Driss Zoukhri
52	Overview of Electrolyte and Fluid Transport across the Conjunctiva	Oscar Candia
53	Conjunctival Goblet Cells	Robin Hodges
54	OCULAR MUCINS	Monica Berry
55	Conjunctiva Immune Surveillance	Erich Knop
56	Tear drainage	Friedrich Paulsen
57	Defense mechanisms of tears and ocular surface	Alison McDermott
58	Cornea Overview	Penny Asbell
59	The Corneal Epithelium: Cell Biology and Basic Science	Mary Ann Stepp
60	Corneal Epithelium: Wound Healing Junctions, Attachment to Stroma Receptors, Matrix Metalloproteinases, Intracellular Communications	Elizabeth Fini
61	Corneal epithelium: response to infection	Linda Hazlett
62	Corneal epithelium: transport and permeability	Peter Reinach
63	The Ocular Surface: The Surgical Treatment for Corneal Epithelial Stem Cell Deficiency, Corneal Epithelial Defect, and Peripheral Corneal Ulcer	Noriko Koizumi
64	Refractive surgery and inlays	Rudy Nuijts
65	Stem cells of ocular surface	James Funderburgh
66	Contact lenses	Fiona Stapleton
67	Imaging of the Cornea	Stephen Kaufman
68	Corneal nerves: anatomy	Carl Marfurt
69	Corneal nerves: function	Carlos Belmonte
70	Corneal stroma	James Funderburgh
71	Corneal dystrophies	Natalie Afshari
72	Corneal imaging - clinical	Roger Steinert
73	Corneal scars	Daniel Dawson
74	Corneal endothelium overview	David Whikehart
75	Corneal endothelium signaling mechanisms	Joseph Bonnano
76	Corneal endothelium regulation of proliferation	Ula Jurkunas
78	Artifical cornea	May Griffith
79	Blinking mechanism	Charles McMonnies
80	Drug delivery to cornea and conjunctiva–esterase and protease directed prodrug design	Ashim Mitra
81	Inflammation of conjunctiva	Teruo Nishida
82	Knock out mice models: cornea, conjunctiva, lacrimal gland	Winston Kao
83	Gene therapy	Rajiv Mohan
84	Lids: anatomy, pathophysiology and mucocutaneous junction	Ted Wojno
85	The role of the ciliary body in aqueous humor dynamics. Structural aspects	Ernst Tamm
86	Ion transport in the ciliary epithelium	Olaf Strauss
88	Neuroendocrine properties of the ciliary epithelium	Miguel Coca-Prados
89	Control of Aqueous Humor Flow	Jay McLaren
90	Ciliary blood flow and its role in aqueous humor formation	Jeffrey Kiel
91	Pharmacology of aqueous humor formation	Carol Toris
92	Functinal morphology of the trabecular meshwork	Ernst Tamm
93	Biomechanics of Aqueous Humor Outflow Resistance	Mark Johnson
94	The Biology of Schlemm’s Canal	Dan Stamer
95	The Fibrillar Extracellular Matrix of the Trabecular Meshwork	Donna Peters
96	The role of proteoglycans in the trabecular meshwork	Ted Acott
97	Regulation of Extracellular Matrix Turnover in the Aqueous Humor Outflow Pathways	Rudolf Fuchshofer
98	The Cytoskeletal Network Of The Trabecular Meshwork	Paul Kaufman
99	Steroid-Induced Ocular Hypertension and Effects of Glucocorticoids on the Trabecular Meshwork	Abbot Clark
100	Myocilin	Mike Fautsch
101	The role of oxidative stress in the trabecular meshwork	Pedro Gonzalez
102	Biological Properties of the Trabecular Meshwork Cells	Paul Russell
103	Uveoscleral outflow	Albert Alm
104	Pharmacology of the aqueous humour outflow	Kathryn Cracknell
106	The development of the aqueous humor outflow pathways	Ernst Tamm
108	Immunological Aspects of Aqueous Humor Turnover	Claus Cursiefen
110	Biomechanics of the optic nerve head	J. Crawford Downs
112	Structural Changes in the Trabecular Meshwork with POAG	Elke Luetjen-Drecoll
113	Primary Open Angle Glaucoma	Detlev Spiegel
114	Pseudoexfoliation syndrome and glaucoma	Ursula Schlotzer-Schrehardt
115	Pigment Dispersion Syndrome and Pigmentary Glaucoma	Robert Ritch
116	IOP and damage of ON axons	Robert Nickells
117	Retinal Ganglion Cell Apoptosis and Neuroprotection	Francesca Cordeiro
118	The Genetics of Primary Open-Angle Glaucoma	Rand Allingham
119	Molecular genetics of congenital and juvenile glaucoma	Michael Walter
120	Animal models of glaucoma	Stanislav Tomarev
121	Concept of angiogenic privilege	Claus Cursiefen
122	Angiogenesis in response to hypoxia	H Okano
123	Angiogenesis in inflammation	Zoltan Szekanecz
124	Angiogenesis in wound healing	Omaida Velazquez
125	Hemangiogenesis vs lymphangiogenesis	Diane Bielenberg
126	Innate immunity and angiogenesis	Ralph Kelly
128	Molecular mechanisms of angiostasis	Raghu Kalluri
129	Stability and functional integrity of new blood vessels	Akiyoshi Uemura
130	Vessel Regression	Hans-Peter Hammes
131	Blood:retinal barrier	Jose G. Cunha-Vaz
132	RPE barrier	Lawrence J Rizzolo
133	Properties and Functions of the vessels of the Ciliary Body	Susan Kidson
136	Anatomy and Regulation of the Optic Nerve Blood Flow	Alon Harris
137	BREAKDOWN OF THE BLOOD-RETINAL BARRIER	Stanley Vinores
138	Breakdown of the RPE blood-retinal barrier	Mary Elizabeth Hartnett
139	Macular edema	Robert Frank
140	Central retinal vein occlusion	Sohan Hayreh
141	Pathological retinal angiogenesis	Anthony Adamis
142	Development of the Retinal Vasculaure	Tailoi Chan-Ling
143	Choroidal Neovascularization	Scott Cousins
144	The Vascular Stem Cell	Maria Grant
145	CORNEAL ANGIOGENESIS	Dimitri Azar
146	Avascularity of the cornea	Jayakrishina Ambati
147	Retinal Pigment Epithelial - Choroid Interactions	Knatokie Ford
149	Pericytes and Microvascular Remodeling: Regulation of Retinal Angiogenesis	Ira Herman
150	Evolution of opsins	Todd Oakley
151	Genetic dissection of invertebrate phototransduction	Baruch Minke
152	Phototransduction in Limulus photoreceptors	Richard Payne
153	MICROVILLAR AND CILIARY PHOTORECEPTORS IN MOLLUSCAN EYES	Enrico Nasi
154	The Photoresponse in Squid	Jane Mitchell
155	The physiology of photoreceptor synapses and other ribbon synapses	Wallace B. Thoreson
157	Limulus eyes and their circadian regulation	Barbara Battelle
158	Circadian rhythms in the fly's visual system	Elzbieta Pyza
159	Fish retinomotor movements	Beth Burnside
160	The circadian clock in the retina regulates rod and cone pathways	Stuart Mangel
161	Circadian Regulation of Ion Channels in Photoreceptors	Gladys Ko
162	Circadian Metabolism in the Chick Retina	P. Michael Iuvone
163	The Colorful Visual World of Butterflies	Francesca Frentiu
164	Polarized-Light Vision in Land and Aquatic Animals	Tom Cronin
165	Zebra fish as a model for understanding retinal diseases	Susan Brockerhoff
166	Zebra fish - Retinal Development and Regeneration	David R. Hyde
167	Xenopus laevis as a model for understanding retinal diseases	Orson Moritz
168	Retinal Degeneration Through the Eye of the Fly	Nansi Colley
169	Developmental Anatomy of the Retinal and Choroidal Vasculature	Joe G Hollyfield
170	Post-Golgi trafficking and ciliary targeting of rhodopsin	Dusanka Deretic
171	PHYSIOLOGICAL ANATOMY OF THE RETINAL VASCULATURE	Sohan Hayreh
172	Physiological Anatomy of the Choroidal Vasculature	Sohan Hayreh
173	Rod and cone photoreceptor cells: inner and outer	David S Williams
175	Rod and cone photoreceptor cells: outer segment membrane renewal	David S Williams
176	Light-driven translocation of signaling proteins in vertebrate photoreceptors	Vadim Arshavsky; Peter Calvert
177	Rod photoreceptor cells: soma and synapse	Robert Smith
178	Cone photoreceptor cells: soma and synapse	Robert Smith
179	Morphology of interneurons: horizontal cells	Leo Peichl
180	Morphology of interneurons: bipolar cells	Silke Haverkamp
181	Morphology of interneurons: amacrine cells	Enrica Strettoi
182	Morphology of interneurons: interplexiform cells	Doug Mcmahon
183	Phototransduction: rhodopsin	Kris Palczewski
184	RETINAL PIGMENT EPITHELIUM: CYTOKINE MODULATION OF EPITHELIAL PHYSIOLOGY	Sheldon Miller
185	Phototransduction: the visual cycle	Gabriel Travis
186	Phototransduction: Phototransduction in Rods	Yingbin Fu
187	Phototransduction: inactivation in rods	Vsevolod Gurevich
188	Phototransduction: adaptation in rods	Trevor Lamb
189	Phototransduction: phototransduction in cones	Vladimir Kefalov
190	Phototransduction: inactivation in cones	Vsevolod Gurevich
191	Phototransduction: adaptation in cones	Trevor Lamb
192	Circadian Photoreception	Ignacio Provencio
193	Retinal Cannabinoids	Stephen Yazulla
194	Information Processing in the Retina	Frank Werblin
195	Information processing: horizontal cells	Arlene A. Hirano
196	Information processing: bipolar cells	Samuel Wu
197	Information processing: amacrine cells	Robert Marc
198	Information processing: ganglion cells	Thomas Muench
199	Information processing: contrast sensitivity	Jonathan, B. Demb
200	Information processing: direction sensitivity	Z. Jimmy Zhou
201	Information processing: retinal adaptation	Kenneth Alexander
202	Glutamate Receptors in Retina	Malcolm Slaughter
203	GABA Receptors in the Retina	Stephen Yazulla
204	THE ROLE OF ACETYLCHOLINE AND ITS RECEPTORS IN RETINAL PROCESSING	Kent T Keyser
205	Neurotransmitters and receptors: dopamine receptors	P. Michael Iuvone
206	Neurotransmitters and receptors: melatonin receptors	Allan Wiechmann
207	Neuropeptides: localization	Nicholas Brecha
208	Neuropeptides: function	Nicholas Brecha
209	Primary photoreceptor degenerations: terminology	Richard G Weleber
210	Primary photoreceptor degenerations: retinitis pigmentosa	Richard G Weleber
211	Secondary photoreceptor degenerations: age-related macular degeneration	L Johnson
212	Secondary photoreceptor degenerations	Michael Gorin
213	Retinal Vasculopathies: Diabetic Retinopathy	Jayakrishina Ambati
214	Retinopathy of Prematurity	Mary Elizabeth Hartnett
215